J Cosmet Med 2021; 5(2): 108-110
Published online December 31, 2021
Department of Plastic and Aesthetic Surgery, Xinhua Hospital Affiliated to Dalian University, Dalian, China
Correspondence to :
Chen Zhang
E-mail: neilzhang@sina.com
© Korean Society of Korean Cosmetic Surgery & Medicine
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Botulinum toxin injections are a popular cosmetic procedure because of their satisfactory results, less downtime, and limited side effects. However, some rare adverse events may occur soon after the procedure. Here, we present the case of a patient who developed severe facial edema after her first botulinum toxin injections for frontal wrinkles. A 28-year-old female was injected with 20 units of botulinum toxin to eliminate her frontal and glabella wrinkles. The injection was completed smoothly and uneventfully. Six hours post injection, the patient’s face started to swell up and redden with a burning feeling, and the swelling progressively worsened progressively. She was diagnosed with Type I hypersensitivity after the level of immunoglobulin E in her blood serum was tested. Her symptoms were controlled by treatment with systemic corticosteroids and antihistamines in the next two days and the patient was cured with no recurrence during a 2-year follow-up. This case demonstrates the possibility of developing severe facial edema after botulinum toxin injection. Treatment with systemic corticosteroids and oral antihistamines would help to control this allergic adverse effect.
Keywords: adverse effects, botulinum toxins, cosmetics, edema, face
J Cosmet Med 2021; 5(2): 108-110
Published online December 31, 2021 https://doi.org/10.25056/JCM.2021.5.2.108
Copyright © Korean Society of Korean Cosmetic Surgery & Medicine.
Department of Plastic and Aesthetic Surgery, Xinhua Hospital Affiliated to Dalian University, Dalian, China
Correspondence to:Chen Zhang
E-mail: neilzhang@sina.com
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Botulinum toxin injections are a popular cosmetic procedure because of their satisfactory results, less downtime, and limited side effects. However, some rare adverse events may occur soon after the procedure. Here, we present the case of a patient who developed severe facial edema after her first botulinum toxin injections for frontal wrinkles. A 28-year-old female was injected with 20 units of botulinum toxin to eliminate her frontal and glabella wrinkles. The injection was completed smoothly and uneventfully. Six hours post injection, the patient’s face started to swell up and redden with a burning feeling, and the swelling progressively worsened progressively. She was diagnosed with Type I hypersensitivity after the level of immunoglobulin E in her blood serum was tested. Her symptoms were controlled by treatment with systemic corticosteroids and antihistamines in the next two days and the patient was cured with no recurrence during a 2-year follow-up. This case demonstrates the possibility of developing severe facial edema after botulinum toxin injection. Treatment with systemic corticosteroids and oral antihistamines would help to control this allergic adverse effect.
Keywords: adverse effects, botulinum toxins, cosmetics, edema, face
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