J Cosmet Med 2020; 4(2): 75-79  https://doi.org/10.25056/JCM.2020.4.2.75
NuEra tight: efficacy and safety in the treatment of the appearance of cellulite with minimal downtime
Sergey Y Turin, MD1, Christopher J Micallef, DO2, Clark F Schierle, MD, PhD1
1Division of Plastic and Reconstructive Surgery, Northwestern Feinberg School of Medicine, Chicago, IL, United States,
2Division of Plastic and Reconstructive Surgery, University of Illinois at Chicago School of Medicine, Chicago, IL, United States
Sergey Y Turin
E-mail: Sergey.Turin@northwestern.edu
Received: November 25, 2020; Revised: December 10, 2020; Accepted: December 12, 2020; Published online: December 31, 2020.
© Korean Society of Korean Cosmetic Surgery. All rights reserved.

cc This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Cellulite is a complex aesthetic problem caused by a complex interplay of dermal-fascial septae, lipodystrophy, and inadequate skin elasticity, but reliable solutions for this condition remain elusive.
Objective: To evaluate a novel radiofrequency-based body contouring device cleared by the FDA for the temporary improvement in the appearance of cellulite in the thighs and abdomen (NuEra; Lumenis, Ltd., Yokneam, Israel).
Methods: A prospective cohort trial was designed to first collect subjective patient and provider reported outcome measures of safety, comfort, and efficacy of the NuEra system in treatment of thigh cellulite in 9 participants. Following review of this data, the second portion of the trial was conducted using the NuEra system to treat the abdominal area in the same patients, collecting anthropometric measurements using a 3-dimensional imaging system (Vectra M3; Canfield, Parsippany, NJ, USA). Treatment protocol specified 5 treatments at approximately 1 week intervals with a final treatment after a 6 week delay. Results were assessed at the time of the treatments and at two month following the last treatment. Likert scales were used to evaluate subjective provider and patient experience and a standardized cellulite assessment scale was used to rate the pre and post treatment photographs.
Results: Patients rated the overall level of comfort at 4.3 and satisfaction as 3.3 on a 5-point scale. Pain scale scores during treatment averaged 1.4 on a 5-point scale. Providers reported very high levels of satisfaction with the ease of the treatment (4.3 on a 5-point scale). Evaluation of standardized photographs showed an average improvement of 0.53 (standard deviation [SD]=0.53), with the average pre-treatment score of 2.2 (SD=0.62) and post-treatment score of 1.64 (SD=0.68). The average reduction in waist and hip circumference measurements was 0.99 cm (SD=2.68 cm) and 0.71 cm (SD=1.44 cm).
Conclusion: Radiofrequency based body contouring is a safe, effective, and well tolerated treatment for thigh cellulite.
Keywords: body contouring; cellulite; noninvasive; radiofrequency; skin texture
  1. Davis DS, Boen M, Fabi SG. Cellulite: patient selection and combination treatments for optimal results-a review and our experience. Dermatol Surg 2019;45:1171-84.
    Pubmed CrossRef
  2. Hexsel D, Mazzuco R. Cellulite. In: Tosti A, Hexsel D, editors. Update in cosmetic dermatology. Berlin: Springer; 2013. p. 2132.
  3. Callaghan DJ III, Robinson DM, Kaminer MS. Updates in cellulite reduction. Adv Cosmet Surg 2018;1:45-53.
  4. Sadick N. Treatment for cellulite. Int J Womens Dermatol 2018;5:68-72.
    Pubmed KoreaMed CrossRef
  5. Hexsel D, Fabi SG, Sattler G, Bartsch R, Butterwick K, Casabona G, et al. Validated assessment scales for cellulite dimples on the buttocks and thighs in female patients. Dermatol Surg 2019;45 Suppl 1:S2-11.
    Pubmed CrossRef
  6. Weiss ET, Barzilai O, Brightman L, Chapas A, Hale E, Karen J, et al. Three-dimensional surface imaging for clinical trials:improved precision and reproducibility in circumference measurements of thighs and abdomens. Lasers Surg Med 2009;41:767-73.
    Pubmed CrossRef
  7. The American Society for Aesthetic Plastic Surgery. Cosmetic (aesthetic) surgery national data bank statistics [Internet]. Garden Grove (CA): The American Society for Aesthetic Plastic Surgery; c2018 [cited 2019 Jun 20]. Available from: https://www.surgery.org/sites/default/files/ASAPS-Stats2018_0.pdf.
  8. Hsu TS, Kaminer MS. The use of nonablative radiofrequency technology to tighten the lower face and neck. Semin Cutan Med Surg 2003;22:115-23.
    Pubmed CrossRef
  9. Araújo AR, Soares VP, Silva FS, Moreira Tda S. Radiofrequency for the treatment of skin laxity: mith or truth. An Bras Dermatol 2015;90:707-21.
    Pubmed KoreaMed CrossRef
  10. Nassab R. The evidence behind noninvasive body contouring devices. Aesthet Surg J 2015;35:279-93.
    Pubmed CrossRef
  11. Wanitphakdeedecha R, Iamphonrat T, Thanomkitti K, Lektrakul N, Manuskiatti W. Treatment of abdominal cellulite and circumference reduction with radiofrequency and dynamic muscle activation. J Cosmet Laser Ther 2015;17:246-51.
    Pubmed CrossRef
  12. Emilia del Pino M, Rosado RH, Azuela A, Graciela Guzmán M, Argüelles D, Rodríguez C, et al. Effect of controlled volumetric tissue heating with radiofrequency on cellulite and the subcutaneous tissue of the buttocks and thighs. J Drugs Dermatol 2006;5:714-22.
  13. Manuskiatti W, Wachirakaphan C, Lektrakul N, Varothai S. Circumference reduction and cellulite treatment with a TriPollar radiofrequency device: a pilot study. J Eur Acad Dermatol Venereol 2009;23:820-7.
    Pubmed CrossRef
  14. Fitzpatrick R, Geronemus R, Goldberg D, Kaminer M, Kilmer S, Ruiz-Esparza J. Multicenter study of noninvasive radiofrequency for periorbital tissue tightening. Lasers Surg Med 2003;33:232-42.
    Pubmed CrossRef

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